The hepatic lobule
WebAlthough various liver chips have been developed using emerging organ-on-a-chip techniques, it remains an enormous challenge to replicate the liver lobules with self-assembled perfusable hepatic sinusoid networks. Herein we develop a lifelike bionic liver lobule chip (LLC), on which the perfusable hepatic sinusoid networks are achieved using a … WebThe hepatic lobule is the structural unit of the liver. It consists of a roughly hexagonal arrangement of plates of hepatocytes radiating outward from a central vein in the center. At the vertices of the lobule are regularly distributed portal triads, containing a bile duct and a terminal branch of the hepatic artery and portal vein. ...
The hepatic lobule
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WebThe hepatic lobule is the anatomic unit of the liver. In the anatomic model, liver lobules are organized into irregular polygons demarcated by connective tissue and composed of … WebThe liver lobule is a hexagonal area of tissue, and contains a single central vein which drains blood away from the liver lobule (via the hepatic vein which eventually drains into the …
Web21 Apr 2024 · The Anatomical Record. This article reviews hepatic fibrosis‐associated histopathology of aged cadavers (mean age 82 years). A study of 68 livers identified steatosis in 35.5%, central vein fibrosis in 49.2%, perisinusoidal fibrosis in 63.2%, portal tract fibrosis in 47.7%, septa formation in 44.1%, bridging fibrosis in 30.8%, and cirrhosis ... Webhepatocytes. Drainage from the lobule is through the central hepatic venule. Each hexagonal lobule has a central portal tract containing branches of the hepatic artery, portal vein and …
Web11 May 2024 · Hepatic: of or relating to the liver Physiology Drug metabolism Phase 1 reactions increase polarity and water solubility of compounds through oxidation, reduction and hydrolysis through the cytochrome p450 system Phase 2 reactions create less toxic byproducts through transferase reactions and conjugations Lipid metabolism Web29 Nov 2005 · These are grouped around a central vein, which opens into a branch of the hepatic veins. The lobule is surrounded by a capillary plexus in which branches of the …
WebHepatic stellate cells (HSCs; also called as vitamin A-storing cells, lipocytes, interstitial cells, fat-storing cells, Ito cells) exist in the space between parenchymal cells and sinusoidal endothelial cells of the hepatic lobule, and store 80% of vitamin A in the whole body as retinyl palmitate in lipid droplets in the cytoplasm.
Web8 May 2024 · The liver plays a role in nearly every organ system in the body. It interacts with the endocrine and gastrointestinal systems by aiding in digestion and metabolism. The liver is the storage location for fat-soluble … furnace humidifier not keeping upWebAbstract This interactive learning module describes the histological architecture of the liver lobule. The three-dimensional presentation and animations facilitate the visualization of the relationships between the basic components of the liver lobule: cells, blood vessels, and bile ducts. The microvasculature is presented in reference to ... github terraform-docsWebIn cross section, a hepatic lobule looks like a side view of a bicycle wheel. The numerous spokes of the wheel are the hepatic ____, which are bordered by cords of hepatocytes. sinusoids The gallbladder has three regions: the ______, ______, and fundus. neck; body Blood leaves the liver through the ______. hepatic veins github terraform aws provider