Tīmeklis2009. gada 1. maijs · Abstract. De novo fatty acid (FA) synthesis resulting from fatty acid synthase (FASN) upregulation is associated with aggressive prostate cancer. FASN overexpression is oncogenic in immortalized prostate epithelial cells and when expressed as a transgene in the murine prostate. Its suppression induces apoptosis … TīmeklisFatty acid synthase enhances colorectal cancer cell proliferation and metastasis via regulating AMPK/mTOR pathway . Fulltext; Metrics; Get Permission; Cite this article; Authors Lu T, Sun L , Wang Z, Zhang Y, He Z, Xu C. Received 24 December 2024. Accepted for publication 25 March 2024
Demethoxycurcumin Modulates Prostate Cancer Cell Proliferation via AMPK ...
Tīmeklis2024. gada 5. janv. · FASN induces inhibitive effects on the AMPK pathway, thus enhancing proliferation, growth, migration, invasion, EMT and relieving apoptosis. … TīmeklisDa Som Lee1,2 iD Tae Hyeon An2,3 iD Hyunmi Kim2,3 iD Eunsun Jung4 iD Gyeonghun Kim5 iD Seung Yeon Oh6 iD Jun Seok Kim7 iD Hye Jin Chun8 iD Jaeeun Jung9 iD Eun-Woo Lee2,3 iD Baek-Soo Han3,10 iD Dai Hoon Han11 iD Yong-Ho Lee8,12 iD Tae-Su Han3,4 iD Keun Hur13 iD Chul-Ho Lee3,14 iD Dae-Soo Kim9 iD Won Kon Kim2,3 iD … song walk around heaven all day
Impairment of Angiogenesis by Fatty Acid Synthase
Tīmeklisto the catalytic region of AMPK.Therefore, we believe that Alisol A could serve as a promising agent for treatment of obesity and its related metabolic diseases. … TīmeklisFASN, a nearly-universal druggable target in many human carcinomas and their precursor lesions, offers new therapeutic opportunities for metabolically treating and preventing cancer. Tīmeklis2024. gada 21. okt. · FASN activation is an early and near universal hallmark of most human carcinomas and their precursor lesions, and is enhanced in a stage … song walk hand in hand with me