Tīmeklisezetimibe localizes at the brush border of the small intestine and inhibits the absorption of cholesterol and thus results in reduced delivery of intestinal cholesterol to the liver. … Tīmeklis2024. gada 1. febr. · Ezetimibe is a useful second-line therapy for hypercholesterolemia that produces a modest reduction in LDL cholesterol compared with statin therapy.3 …
Statins Prescribing information Lipid modification - CKS NICE
Tīmeklis2024. gada 5. febr. · Ezetimibe is a medication used in the management and treatment of hypercholesterolemia. It is among a novel class of selective cholesterol-absorption inhibitors. ... In addition, clinicians should obtain LFTs if hepatotoxicity is suspected, as autoimmune hepatitis associated with ezetimibe requires treatment with … Tīmeklis11 rindas · 2024. gada 10. aug. · Other lipid-lowering agents. CYP3A4 inhibitors. PCSK9 inhibitors (e.g., alirocumab, evolocumab) Add-on therapy for patients who have both … Our representative and wholly-owned subsidiary in the US: AMBOSS MD Inc. … food panda hong kong voucher
statin treatment and abnormal LFTs - General Practice notebook
TīmeklisDo not prescribe ezetimibe to: People with stage 4 or 5 chronic kidney disease (CKD, estimated glomerular filtration rate [eGFR] less than 30 mL/minute/1.73 m 2).; … Tīmeklis2016. gada 1. jūl. · Ezetimibe-statin combination therapy was associated with a lower risk of cardiovascular events than statin monotherapy: 33% of the patients treated with ezetimibe and a statin, and 35% of those treated with a statin alone, had a cardiovascular event within seven years (number needed to treat [NNT]: 50 over 7 … TīmeklisRecheck liver function tests (LFTs) within 3 months of starting treatment, and again at 12 months. Further monitoring is not necessary unless clinically indicated (for … electabuzz counters pokemon go